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Multi-Channel Epithelial Voltage/Current Clamp Systems
Price: $10,683.00
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The VCC MC family of voltage/current clamps is a useful tool for studying transepithelial transport. The larger instruments are the VCC MC6 and new VCC MC8.
The VCC MC6 and VCC MC8 are modular, multichannel voltage/current clamps that can be configured with 2, 4 or 6 and 2, 4, 6 or 8 voltage/current clamp channels, respectively. These instruments are ideally suited for experiments requiring multiple specimens. They offer the distinct advantage of expendability within the same instrument chassis. A very useful feature built-in to both VCC MC6 and VCC MC8 instruments is a master control section. When enabled this section enables the investigator to quickly change the function, mode and meter switches on each clamp module from a single bank of switches on the master control panel. This feature markedly simplifies use of the instrument and removes some of the tedium of continually having to change multiple switches (e.g., changing the meter switch to display current instead of voltage on eight channels). The VCC MC6 is well suited for use either with the EasyMount chamber system (three dual chamber systems placed in series) or the six-channel Harvard/NaviCyte systems). For the latter system, a special 24-lead input module (EP MC6) replaces the individual DM MC6 input modules for making connection to the electrodes. The EP MC6 mounts between the heat block and air manifold on the Harvard/NaviCyte system and must be specified when ordering. The EasyMount system (four dual chamber systems in series) is better suited for use with the eight-channel VCC MC8 instrument. Ussing chamber systems are sold separately.
Features:
- Available with 2, 4 or 6 channels
- 8 Channel Systems available, call for details
Power Requirements 100/125 VAC, 60 Hz or 200/250 VAC, 50 Hz, user selectable
Input Resistance ?109?, differential
Common Mode Rejection ?100 dB
Frequence Response 4-stage adjustment via internal switch
Display 3.5 digit,3/8 in LCD with green backlight for each channel
Transepithelial Voltage±199.9 mV
Transepithelial Current±19.90, ±199.9, ±1999 µA, jumper selectable
Switches Push button, digital switching with LED indicators
Meter Selects current or voltage to be displayed on panel meter
Function Three position switch with LED indicator of state
Zero Function Standby mode, voltage inputs are internally grounded
Open Function Open circuit, voltage inputs are connected to sensing electrodes
Clamp Function Feedback loop is closed to control either current or voltage
Mode Two switches select operating modes
Voltage/Current (I/V) Mode Selects transepithelial voltage or current to be controlled when Function is on Clamp
Remote (REM) Mode Selects control to be from front panel switches or from remote interface
Offset Potential ±10 or ±100 mV, set via precision 10-turn dial, jumper selectable ranges and lighted polarity switch
Fluid Resistance Push-button current injection, compensation set by precision 10-turn dial, jumper selectable ranges
On/Off ‘On’ sends pulse output to clamp, red indicator light
Polarity Selects +, - or bipolar pulses to be generated
Single Pulse Injects single pulse during interval between pulses
Reset Initializes interval timer and injects pulse
Amplitude 0 to 10 mV in 1 mV steps at X1 gain; 0 to 100 mV in 10 mV steps at X10 gain
Period 0.1 to 99.9 sec time period between pulses; set by 3-decade thumbwheel switch
Duration 0.01 to 9.99 sec duration of each pulse; set by 3-decade thumbwheel switch
DC Clamp Level Sets DC holding voltage or current
Voltage Clamp ±100 mV via 10-turn dial, lighted polarity switch
Current Clamp Current gain dependent, 50% of max. displayed current
Master Override Permits control of function, mode, and meter features on all installed clamp channels
Electrode Inputs 5 mm pin tip via DM_MC6 single channel input module, 1 per channel (VCC MC6 and VCC MC8)
2 mm pin tip via electrode panel (EP MC6) for Harvard/Navicyte chamber system (VCC MC6)
Recorder Output Voltage 10 mV/mV, x10 transepithelial voltage
Recorder Output Current Jumper selectable, 1, 10 or 100 mV/µA
Pulse Generator 3 to ±100 mV and 0 to ±1 V
External Input Allows arbitrary analog input signal to be clamped
Remote Interface 25-pin DB connector
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